How does Equelle work?

Equelle's key ingredient, S-equol, works by safely and naturally mimicking estrogen.

As estrogen declines, menopause symptoms go up. S-equol acts like estrogen in your body to help decrease menopause symptoms.

As we age, our bodies gradually produce less of the hormone estrogen.

Estrogen fluctuates during perimenopause and ultimately declines to lower levels through postmenopause, leading to unwanted symptoms.

S-equol shares a similar molecular structure to estrogen, allowing it to bind to the body’s estrogen receptors and mimic the effects of estrogen.

The Science Behind It All

Your body has two main types of estrogen receptors, called alpha receptors and beta receptors.

Alpha receptors are primarily in your breast, ovarian, and uterine tissues.

Beta receptors are primarily in places like the lining of your blood vessels and some parts of your brain.

Estrogen, and estrogen hormone replacement therapies, bind to both alpha and beta receptors.

S-equol has a similar molecular structure to estrogen but mostly binds to beta receptors.

Mimics the benefits of estrogen and relieves menopause symptoms

Mimics the benefits of estrogen and relieves menopause symptoms

No association with breast cancer or other cancers

No association with breast cancer or other cancers

The Power of S-equol

Derived from Soy

S-equol shares a similar shape to estrogen and mimics some of its actions, helping to alleviate menopause symptoms associated with decreased estrogen.

Our proprietary process leaves only small traces of soy compounds remain in the final Equelle product and recreates how S-equol is naturally produced in the body.

S-equol:
Is proven safe by scientific experts
Extensively studied for more than 40 years


S-equol:
Does not affect breast or uterine health
Does not have associations with breast cancer or other cancers
Does not change sex and thyroid hormones

Key Ingredients: S-equol

Other Ingredients: Dicalcium Phosphate, Fermented Soy Germ, Silicon Dioxide, Croscarmellose Sodium, Magnesium Stearate, Coating (Hypromellose, Glycerin, Hydroxypropyl Cellulose), Microcrystalline Cellulose. Contains Soy

During menopause, estrogen levels decrease causing symptoms like hot flashes, sleep difficulties and vaginal irritation. Equelle's active ingredient, S-equol, has a similar structure as estrogen and can mimic some of its actions, helping to ease menopause symptoms.

S-equol is the active ingredient in Equelle. It is a naturally derived compound produced through the fermentation of soy germ and is naturally produced by women in the gut in small amounts. The S-equol used in Equelle is developed using a patented fermentation process that simulates the specific gut conditions needed for certain bacteria to produce S-equol.

Equelle's active ingredient, S-equol, comes from Japan. It is tableted and manufactured in the United States.

Taking Equelle does not impact estrogen levels. Although Equelle’s active ingredient, S-equol, mimics some of the same activities of estrogen by preferentially binding to estrogen receptor beta, Equelle is a dietary supplement free from human & animal hormones and clinical research shows S-equol supplementation reduces the frequency of hot flashes, supports the quality of sleep, reduces bothersome vaginal symptoms like irritation, soreness and itching, and alleviates mood swings.

Your body has two main types of estrogen receptors, called alpha receptors and beta receptors. Alpha receptors are primarily in your breast, ovarian, and uterine tissues. Beta receptors are primarily in places like the lining of your blood vessels and some parts of your brain. Estrogen, and estrogen hormone replacement therapies, bind to both alpha and beta receptors. S-equol has a similar molecular structure to estrogen but mostly binds to beta receptors.

By favoring these beta receptors, S-equol:
● Mimics the benefits of estrogen and relieves menopause symptoms
● Does not increase your risk for breast cancer and is not associated with changes in sex or thyroid hormones or endometrial health

Equelle and its active ingredient, S-equol, have undergone decades of clinical research and development. It has been shown to be safe and is not associated with changes in sex or thyroid hormones, negative effects on endometrial health or breast cancer. In general, taking botanicals or plant-based supplements may result in possible gastrointestinal upset. If you are experiencing any adverse effects, we recommend discontinuing product use and consulting your physician or healthcare professional.

Equelle is safe to take with other foods, supplements, and over-the-counter or prescription medications and will not negatively interact with them. However, Equelle should not be taken if you have a soy allergy or sensitivity. If you are pregnant, nursing, taking any medications and/or hormone therapy (HT), you should consult your healthcare professional before taking this product.

If you're experiencing menopause symptoms like hot flashes, sleep disturbances, vaginal discomfort, and more, Equelle is right for you whether you are in perimenopause, menopause, or postmenopause.

20 years of dedicated research.

Ready to get relief from your menopause symptoms?